Insights

Maximale Vektoren-Ausbeute für Thermo Fisher Scientific VVS

Maximum viral vector yield for Thermo Fisher Scientific VVS

For the first time, Thermo Fisher Scientific VVS (formerly Brammer Bio) is relying on an OPTIMA VFVM isolated filling and closing machine for fill/finish of viral vector products. This provides the Thermo Fisher Scientific group's Viral Vector Contract Development and Manufacturing Organization (CDMO) with a safe turnkey solution and minimal product loss per batch, as well as other benefits.
November 8, 2022
A robot transfers syringes to the subsequent plant zone.

MultiUse Portfolio: Flexible and High Performance

The latest generation of OPTIMA MultiUse equipment processes up to 24,000 containers per hour. The complete MultiUse portfolio covers applications from clinical studies to large batch sizes. The processes are transferrable on a one-to-one scale, up to the highest output, while maintaining precise dosing volumes, and maximizing the product yield and flexibility.
November 8, 2022
Get into production even faster

Get into production even faster

Some filling and packaging challenges need to be dealt with even faster than others. To do this, short delivery times are needed, and this can only be achieved with standardized machine solutions. That is why the tried-and-tested OPTIMA Moduline filling and closing machine is now also available with preconfigured machine modules. The result is a whole host of advantages for machine users.
July 5, 2022
Produce more efficiently and more securely

Produce more efficiently and more securely

For Optima Pharma, from the very beginning digitalization has meant what we implement will create added value for you, our customers. We have developed a broad portfolio of digital solutions with this goal in mind. These solutions are used successfully in the initial systems. Optima has also undergone a massive upgrade in terms of cybersecurity. In the following article, read how pharmaceutical production has become more secure and more efficient in the areas of production data management, maintenance, operator guidance and knowledge transfer.
June 10, 2022
Microdosing at its finest

Microdosing at its finest

A range of test formats are used in diagnostics to detect acute infection and prevent the uncontrolled spread of the SARS-CoV-2 pathogen. At the Marburg site, Siemens Healthineers have recently started a very high quality PCR test on an OPTIMA ImmuFill®. This machine achieves high precision reagent dosing into containers from a dosing volume of 50 µl upwards, and these are then closed and labelled.
March 30, 2022
Retrofit as an opportunity

Retrofit as an opportunity

When systems have seen better days, action is needed. Often numerous parts in the control cabinet are outdated. Once central automation components such as the control system have been discontinued, the clock starts ticking. A timely retrofit avoids a costly total breakdown. And it opens up the opportunity to benefit from the possibilities of digitalization.
February 24, 2022
Green packaging not green-washing

Green packaging not green-washing

Sustainability is a future-oriented issue. The way forward is being set today, and it requires interdisciplinary strategies. It is not always necessary to reinvent the wheel. Two sustainable packaging solutions co-developed at Optima are proof of this. One solution received the German Packaging Award, the other is in the running for the Innovation Award for Climate and Environment by the German Federal Ministry for the Environment.
February 17, 2022
Assembly and packaging system

The start of a new era in bone cement

Heraeus Medical is pursuing ambitious goals. Based in Wehrheim near Frankfurt am Main, the company consistently advances the development of bone cement and has constructed a new building to do just that. Their new bone cement system, manufactured using an assembly and packaging system from Optima Automation, makes work simpler and safer.
January 17, 2022
A new aesthetic for paper hygiene packaging

A new aesthetic for paper hygiene packaging

The paper hygiene products market and its packaging are undergoing massive change. There are three main drivers behind this, says Oliver Rebstock, the Managing Director of Optima Nonwovens. Is there urgent need for action?
January 13, 2022
Catalent Against COVID: A Race Against Time

Catalent against COVID: A race against time

When the pharmaceutical industry started to research vaccines to fight COVID-19 in the spring of 2020, the concern that global manufacturing and packaging capacities would need to be increased arose almost simultaneously. At Catalent Pharma Solutions, a leading development and manufacturing partner to pharmaceutical companies, preparations began to boost vaccine production capabilities.
August 12, 2021
The new CSPE Center in Schwäbisch Hall

CSPE convinces in practical tests

CSPE reduces the time span between designing the system and the start of production. After numerous turnkey projects involving the use of the turbo booster, Gerhard Breu, Chairman of the Optima Pharma Division, takes stock and gives an insight into how CSPE will become even more effective in the future.
August 12, 2021
New INTISO

New INTISO

A new design for isolator technology: Metall+Plastic's INTISO is distinguished by the absence of an HVAC unit and the relocation of cooling and ventilation units from the mechanical floor to the isolator plenum. Even its modular construction is innovative. This article shows the advantages and practical application scenarios that result from this.
August 12, 2021
Flagship Project for Bio-S Strategy

Flagship project for Bio-S strategy

The French pharmaceutical company Servier is expanding its business model. As it moves towards becoming a recognized player in oncology, as part of its BIO-S strategy it is investing in production capacities for biologics and small molecules. The greatest degree of flexibility possible is ensured by a MultiUse line that can fill injectable solutions into syringes and vials.
August 12, 2021
Technology Transfer for Diagnostics in China

Technology transfer for diagnostics in China

One vial, one filling material, one closure – done. But it is not always that simple. In fact, when diagnostic products from bioMérieux are filled, there are four very different media. In 2016, Optima Pharma has developed a specific production line for this. Because of the principle of "never changing a running system", the company has now decided to purchase a duplicate of this system for its Chinese production site in Suzhou.
August 12, 2021
Digital Features for greater Safety

Digital features for greater safety

Optima Pharma has realized a complete vial filling line, including isolators and freeze-drying equipment that is equipped with various digital safety features and mass spectrometry. The customer, a globally active pharmaceutical company, places great value on production reliability and the use of future-oriented technology.
August 12, 2021
International Teamwork for USV India

International teamwork for USV India

The Indian company USV Private Limited was founded in 1961, and now operates in 75 countries around the world – a success story based on entrepreneurial courage and pharmacological expertise. Since September 2019, USV has had two flexible Optima systems in commercial operation at its site in Daman (India).
August 12, 2021
A high-quality Addition to the CDMO Services

A high-quality addition to the CDMO services

The growing biopharma market is an attractive sector for contract manufacturers including Biovian from Finland. The One-Stop-Shop Bio-CDMO has recently expanded its equipment portfolio with a fully automated vial filling line. There were two essential requirements the filling line needed to meet – the system had to minimize losses of valuable therapeutic drugs during filling and fit into the specific physical location in Turku Bioscience Centre.
August 12, 2021
Automation is Key to Saving Lives

Automation is key to saving lives

Personalized tumor treatments are expensive. This particularly applies to individual cancer therapies based on gene-modified T cells. Currently, they are produced manually or, at best, in a partially automated process. In a collaboration project "ProCell for Patient" two hospitals are currently working with Optima Pharma to develop an automated unit for the decentralized production of a CAR-T cell product in treatment centers.
August 12, 2021
Refrigerants: New Ways to reach the Goal

Refrigerants: New ways to reach the goal

How can we slow down and halt climate change? This question only rarely makes it as far as pharmaceutical manufacturing. However, "classic" refrigerants used in freeze-drying systems are harmful to the environment. What is known as the F-gas Regulation set the course for the European Union as early as 2014, and is still impacting the design of freeze-drying plants today. Optima provides solutions.
April 28, 2021
Full Throttle for Vaccine Filling

Full throttle for vaccine filling

When the pharmaceutical industry started research in spring 2020 on vaccines to fight COVID-19, the issue of manufacturing and packaging capacities arose almost at the same time. Requests for suppliers like Optima to provide new sterile fill finish lines with isolators were scheduled to start immediately as emergency drug approvals were granted. 
April 23, 2021
OPTIMA Zero L1

Modularity without limits

Optima's new Zero machine platform is the benchmark for high performance, flexibility and modularity. The OPTIMA Zero L1 configuration is used, for instance, to package feminine hygiene and light incontinence products.
March 9, 2021
The OPTIMA DS1 in production.

High-tech packaging for baby diapers

The young company Viet Sing produces high quality diapers. Happily, the demand for these diapers is increasing. To increase its capacity, the company invested in state-of-the-art German technology, the basic model DS1 from Optima Nonwovens for diaper packaging. The system, which was delivered two months after ordering, is extremely stable and reduces personnel costs by 50 percent.
March 4, 2021
Food Supplements

Food supplements redefinded

A food supplement dosage form committed to health and a positive lifestyle – this was the mission of HERMES PHARMA when presenting its HERMES NutriCaps at the Vitafoods trade show in Geneva in May 2019. These capsules will revolutionize the dietary supplements markets. For the market entry, HERMES PHARMA chose the OPTIMA CFR as its filling machine.
March 4, 2021
sterility test isolator

The STISO with DECOpulse®

Longer operating time and the highest level of pharmaceutical safety is what is on offer from the latest generation of sterility test isolators STISO. This is mainly due to DECOpulse®, the highly efficient, award-winning bio decontamination system. STISO also scores high points for its ergonomic design and the "Plug & Test" principle.
March 4, 2021
Packaging of feminine hygiene products

Growing needs in Asia

Optima offers a highly flexible machine platform for packaging paper hygiene products, starting with entry-level versions and specially designed for the Asian market. The latest version of this series – the OPTIMA FS1 – was exclusively developed for feminine hygiene products. A unique aspect of the machine platform is that entry-level models can initially run semi-automatically and later be upgraded to fully automatic systems.
March 3, 2021
Mission Retrofit accomplished

Mission retrofit accomplished

How do you ensure dairy industry filling systems are ready for the future? Maier Packaging has been answering this question since 1985. In a project at Zott, the company from Bergen am Chiemsee has proven its know-how for retrofitting pre-existing forming, filling and closing systems.
March 3, 2021
PUPSIT Filter

PUPSIT: Test filter!

PUPSIT filter tests are a regulatory requirement in pharmaceutical production for European markets. Which options and strategies there are for this in systems engineering, what needs special attention in the design, and further background information will be presented below.
March 3, 2021
CFL capsules

Fast, flexible and sustainable

The issue of sustainability is becoming more and more important. Recyclable aluminium capsules are very popular. Ahold Delhaize from the Netherlands has also observed this. Consequently, a plastic capsule production line currently under construction has been quickly adapted to meet the requirements for producing aluminum capsules, and this offers a lot of technical features.
March 2, 2021
OPTIMA Pearl

A pearl for Asia

Asian freshwater pearls are highly desirable. They have become the namesake of a new system for packaging feminine hygiene products. OPTIMA "Pearl" has been designed to completely meet the requirements of the global manufacturers producing in Asia, with high output packaging in small volumes, which is typical of the Asian market. What is not so typical is the exceptional priceperformance ratio.
March 2, 2021
Monitoring machine interior cameras (outside)

Three aspects of digitalization

Digitalization involves a lot more than just the collection and networking of data. It means that many tools can be used to help pharmaceutical manufacturers achieve their goals. The focus is on maximizing plant availability and high production reliability. To achieve this, Optima Pharma is pursuing three principal strategies.
February 10, 2021
Robots Master Complexity

Robots master complexity

Robot systems are playing an increasingly important role. These reliable assistants are fully integrated into Optima's filling and packaging systems. All the divisions in the company are using robots in their systems – some of them "cobots", i.e. collaborative robots. However, the scale and utilization can vary greatly.
February 3, 2021
3D printing center

Printing the route to success

Everything, anywhere at any time – that is what consumers are demanding. The consumer goods industry is being turned upside down by the Internet and by influencers. The consequence is sharp shifts in demand. New agile processes are needed to counter this trend.
July 1, 2020
The Denest-Robot offers complex movements

The machine of the future: Smart manufacturing

A machine that comprehensively combines several types of robotics and technology. A machine that uses data for process control and optimization, as well as predictive maintenance. And which will be highly flexible for use in applications that have not yet been identified.
June 30, 2020
Implementation of the innovation project

The machine platform of the future

Frequent product launches. Small batch sizes. Sharp shifts in demand. The demands on manufacturing companies are increasing. Social media and e-commerce accelerate this trend. 
June 25, 2020
Diversity of different Packaging materials

Unique variety

Plastic film packaging for paper hygiene products can be relied on protect the product and serve its purpose in a dependable way. This packaging is very efficient and the process is a stable one, but the market is changing.
June 18, 2020
Future EGS PRO with FS4-24

High-tech for the high care sector

Optima Consumer has developed an innovative concept for the fully automated evacuation, gassing and seaming of baby milk powder containers. This machine concept is the result of extensive market research and it meets the requirements of the infant formula market.
June 15, 2020
OPTIMA OSR

The 100 percent solution

The issue of sustainability is finally here. Packaging has shifted its focus. As a packaging machine manufacturer, we are facing new challenges but nonetheless, ones that can be resolved, by using sustainable, fully recyclable materials that meet the same or higher standards and deliver equivalent result.
May 25, 2020
Digitalization

Optima Total Care goes digital

The aim of the program, which in the future will bring together the Basic and Smart Services, is to provide customers with rapid, efficient support –  from installation, monitoring and maintenance through to retrofitting their systems.
May 15, 2020
high-speed isolator plant for pre-filled syringes

Isolator launch in South Korea

To date, very few filling and capping machines with isolator technology have been installed in South Korea, let alone in Asia. All of this will soon change. Both Oh-sung Na (Aprogen Biologics) and Peter Kim (Optima Korea) are certain of it because Aprogen is one of the pioneers of this new development.
April 30, 2020
Virtualization

Future-proof thanks to virtualization

Pharma 4.0 requires the networking of production systems. Existing systems are also future-proof thanks to virtualization. 
January 31, 2020

7 for Siemens Healthineers – interview about the mega project

Seven systems, consisting of six lines and a closing machine, are currently under development for Siemens Healthineers and are being installed step by step on two continents.
January 31, 2020
The new CSPE Center in Schwäbisch Hall

CSPE: Turbo boost for turnkey

This process significantly shortens the delivery and commissioning times of complex turnkey systems, and numerous projects have already benefited from it.
December 19, 2019
More than 20 cosmetics are processed with the flexible packaging system.

Cosmeceuticals from Pierre Fabre: With a touch of pharma

Cosmeceuticals are trendy. The medical cosmetics are manufactured by Pierre Fabre, among others.
October 7, 2019
Cobots – robots that are able to work around humans

The future is modular

Read our newsroom article to find out why modularity is booming.  
August 12, 2019
Christina Weitze and Jan Buck creating the simulation model

Virtual testing, real progress

Christina Weitze and Jan Buck explain how virtual machine models improve software quality. 
August 12, 2019
Full speed ahead in Asia

Full speed ahead in Asia

Optima Nonwovens has quadrupled its presence in customer service and offers new machine technology.
August 1, 2019
Dr. Georg Pfeifer from Optima Nonwovens and Joachim Dittrich from Optima Consumer

Five questions on digitalization

Dr. Georg Pfeifer and Joachim Dittrich on the need to focus on the digital revolution, the fears of machine operators and the ability to learn "stupid" AI.
August 1, 2019
Product optimization

OPAL in use at Violeta

How a brief visit became a success story
February 28, 2019
Everything flows smooth with Water Filters

Everything flows smooth with water filters

Filtration solution for Brita installed in China
December 17, 2018

Turnkey down to the finest detail

Major Project with Teva
December 17, 2018
The carton can is directly manufactured in the production facility

InlineCan - perfect packaging for tobacco

Hands-on insight at JTI – the InlineCan proves to be the ideal tobacco packaging.
October 23, 2018
Digitalisation

Process reliability through digital technologies

Digital technologies offer great opportunities for the future.
October 22, 2018
Flow simulation

Decontamination: Straight to the finish line

Substantial increase of machine availability for pharmaceutical machinery with reduced H2O2 consumption.
September 19, 2018
Semi-annual maintenance and service

Dream-team: Swissfillon and the MultiUse machine

Do you have highly potent, very expensive or extremely difficult to fill medical products? The contract filler, Swissfillon, was founded just for you. 
July 2, 2018

Open, integrated and tamper-proof

Do you have highly potent, very expensive or extremely difficult to fill medical products? The contract filler, Swissfillon, was founded just for you. 
July 2, 2018
Fast, faster, MDC300 advanced

Fast, faster, MDC300 advanced

Everything from One Supplier: OPTIMA life science completes a Complex Turnkey Project
June 26, 2018

Coffee capsules: The nitrogen economy package

Coffee is a delicate product. In order to prevent the oxidation of the coffee in portion packs, nitrogen gas is used during dosing until the capsules are sealed and the oxygen is removed. 
February 20, 2018
OPTIMA Total Care: Life Cycle Based Services

OPTIMA Total Care: Life cycle based services at a glance 

With its new Optima Total Care portfolio, Optima pushes service to a new level. Service in each phase of the machine life cycle supports production efficiency. 
January 8, 2018
OPTIMA Total Care: Life Cycle Based Services

OPTIMA Total Care: Life cycle based services at a glance 

With its new Optima Total Care portfolio, Optima pushes service to a new level. Service in each phase of the machine life cycle supports production efficiency. 
January 8, 2018

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